The works
Founded in 1871 in Valognes in the Cotentin by the two Bretel brothers, the company had 17 factories by 1933, mainly in the Manche department.
Two toothpaste powders to be used simultaneously. One whitens, the other sanitizes. Bi-Oxyne is manufactured by the Bi-Oxyne toothpaste company in Paris.
The Republic of Isère and the Southeast is a daily newspaper covering the Dauphiné and Savoy regions, headquartered in Grenoble. It had a circulation of 12,000 copies in 1927.






